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oncology

How Can the Side Effects of Oncology Treatment Be Managed?

September 17, 2026 | 5 min read

Oncology treatments in particular chemotherapy, radiotherapy, and targeted therapies aim to control cancerous cells but can also affect healthy cells and give rise to various side effects. Managing these side effects plays an essential role not only in the success of the treatment but also in the patient's quality of life. To address them effectively, a multidisciplinary approach is necessary. Collaboration between oncologists, dietitians, psychologists, and, where needed, rehabilitation specialists allows for more structured and tailored follow-up. It is fundamental to develop a personalised side-effect management plan that takes into account the individual characteristics of the patient, the stage of the disease, and the therapeutic protocol being applied. This plan aims not only to alleviate symptoms but also to maintain the patient's independence and to improve their adherence to the treatment.

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The management of side effects also relies on early detection and regular monitoring. It is important that patients observe changes in their body carefully and communicate them to the medical team. Symptoms such as loss of appetite, fatigue, nausea, or skin changes may seem minor at first but can worsen over time. Early intervention thus helps to prevent more severe complications. Psychological support is also an essential component of this comprehensive care. Prolonged treatments can give rise to stress, anxiety, or depression, which can intensify the perception of physical effects. It is therefore indispensable to adopt a holistic approach that addresses both the physical and psychological needs of the patient.

How Can Chemotherapy-Related Nausea and Fatigue Be Reduced?

Nausea, often accompanied by vomiting, is among the most common side effects of chemotherapy. It results from the action of the medication on the digestive system and the central nervous system. Today, effective antiemetic treatments are available and are generally administered preventively before chemotherapy. Diet also plays a determining role in the management of these symptoms. It is recommended to avoid heavy, fatty, or spicy foods and to favour light, easily digestible meals. Splitting meals into small portions spread throughout the day helps to reduce digestive strain whilst maintaining a sufficient energy intake. Furthermore, consuming food at room temperature or cold can reduce sensitivity to odours and help to lessen nausea.

Chemotherapy-related fatigue is another very common and particularly taxing side effect, often associated with a sense of physical and mental exhaustion. To manage it more effectively, it is advisable to avoid complete inactivity and to incorporate light physical activities into the daily routine. Short walks, breathing exercises, or low-intensity activities can help to stabilise energy levels. Maintaining a regular sleep pattern and ensuring quality rest are equally essential. Rather than long daytime naps, it is preferable to opt for short periods of rest in order to preserve nighttime sleep. From a nutritional standpoint, a diet rich in protein and iron supports the body's recovery. In cases of severe fatigue, it is important to investigate underlying causes, such as anaemia, and to put appropriate treatment in place.

How Can Hair Loss and Skin Problems Be Managed?

Chemotherapy-related hair loss is a striking side effect, both physically and psychologically. Hair follicles, being rapidly dividing cells, are particularly sensitive to treatment, which leads to temporary hair loss. Although it is not always possible to prevent this, certain methods can help to lessen its impact. Scalp cooling caps, for example, reduce blood flow to the scalp and limit the exposure of the follicles to the medication. In addition, it is recommended to handle the hair gently, to avoid aggressive brushing, and to limit exposure to excessive heat. The use of wigs, headscarves, or hats can also help patients to cope better with this phase on an emotional level.

Skin problems are also common during oncology treatments and often manifest as dryness, heightened sensitivity, redness, or irritation. These symptoms result from the disruption of the skin's cell renewal process. To preserve skin health, regular use of moisturising products is essential. It is advisable to choose products suited to sensitive skin, free from fragrance and alcohol. The skin also becomes more vulnerable to the sun's rays, which makes it important to apply a high-factor sun protection and to avoid prolonged exposure. It is also recommended to favour lukewarm rather than hot showers in order to prevent the skin from drying out. If symptoms persist or worsen, a dermatological consultation allows the skincare to be adapted without compromising the continuation of treatment.

How Can Weakening of the Immune System Be Prevented?

Oncology treatments can weaken the immune system, as they affect not only cancerous cells but also the white blood cells responsible for defending the body against infection. This leaves patients more vulnerable to infectious agents. To reduce this risk, it is essential to observe strict hygiene practices. Frequent handwashing, avoiding crowded or high-risk environments, and maintaining good food hygiene are all fundamental measures. It is recommended to avoid raw or insufficiently cooked foods and to ensure the quality and cleanliness of the food consumed. These precautions are particularly important during the periods when immunity is at its weakest.

Strengthening the immune system also involves a balanced diet and a healthy lifestyle. Nutrition rich in vitamins and minerals supports the body's defence mechanisms. Vitamin C, zinc, and protein intake play a key role in cell regeneration and immune response. Adequate hydration also helps to eliminate toxins and to maintain physiological balance. Quality sleep and stress management are equally essential, as they directly influence immune function. In some cases, specific treatments such as growth factors may be prescribed under medical supervision. All of these measures together help to enable patients to undergo their treatment under safer and more comfortable conditions.